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By months 2 to 3, the injury shows active healing progress and training can resume progressively

Timeline: when patients notice changes The first changes most patients report are sleep-related, typically improved sleep depth and morning energy levels, appearing within weeks two to three of the first cycle

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While a causal relationship has not been established, patients with depression or other psychiatric conditions should be monitored for changes in mood or behavior, particularly during the initial weeks of treatment or following dose adjustments